2013 Chemical Communications

ChemCommQuantum dot-DNA origami binding: A single particle, 3D, real-time tracking study”, K. Du, S. Ko, G. M. Gallatin, H. P. Yoon, J. A. Liddle, and A. J. Berglund, Chemical Communications 49, 909-909, 2013

1. Center for Nanoscale Science and Technology, National Institute of Standards and  Technology, Gaithersburg, MD 20899, USA.
2. Maryland Nanocenter, University of Maryland, College Park, MD 20742, USA

ABSTRACT. The binding process of quantum dots and DNA origami was monitored using a 3D, real-time, single-particle tracking system. Single-molecule binding events were directly observed and precise measurements of the diffusion coefficient and second-order photon correlation function, g2(s), were combined to distinguish free quantum dots from different conjugates of nQdot-origami.